Mitochondria-specific phosphorescent imaging and tracking in living cells with an AIPE-active iridium(III) complex.
نویسندگان
چکیده
An AIPE-active iridium(III) complex was found to possess high specificity for mitochondria, superior photostability, low cytotoxicity, and high resistance to the loss of mitochondrial membrane potential. Thus, this complex can be used for mitochondrial imaging and tracking in living cells.
منابع مشابه
A cationic iridium(III) complex showing aggregation-induced phosphorescent emission (AIPE) in the solid state: synthesis, characterization and properties.
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Three cationic iridium complexes containing 4,7-bis(3,6-di-tert-butyl-9H-carbazol-9-yl)-1,10-phenanthroline (L(1)) and 4,7-bis(3',6'-di-tert-butyl-6-(3,6-di-tert-butyl-9H-carbazol-9-yl)-3,9'-bi(9H-carbazol)-9-yl)-1,10-phenanthroline (L(2)) as the ancillary ligands, namely, [Ir(ppy)(2)(L(1))]PF(6) (1), [Ir(ppy)(2)(L(2))]PF(6) (2) and [Ir(oxd)(2)(L(2))]PF(6) (3) (ppy is 2-phenylpyridine, oxd is 2...
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عنوان ژورنال:
- Chemical communications
دوره 49 94 شماره
صفحات -
تاریخ انتشار 2013